AMD Instinct MI300

Review Cycle

February 2026

The Verdict

Executive Summary

The AMD Instinct MI300 is a high-performance accelerator designed for generative AI workloads and HPC applications. Built on the 5 nm process, the MI300 series delivers leadership performance, significantly improving over previous generations of AMD Instinct accelerators. The MI300 series includes two models: the MI300A and MI300X, each tailored to specific use cases. The MI300X GPU delivers up to 1.6X more performance than the Nvidia H100 in AI inference workloads and offers similar performance in training work. The MI300A APU provides a balanced architecture for a wide range of workloads. With its high-performance capabilities and advanced architecture, the AMD Instinct MI300 series is poised to revolutionize the field of AI and HPC. The MI300 series is designed to work seamlessly with AMD EPYC 9004 series processors, offering exceptionally high performance for HPC and AI workloads. The 8U Universal GPU server, which includes eight AMD Instinct MI300X accelerators and dual AMD EPYC 9004 series processors, is an example of the high-performance systems that can be built with the MI300 series.

Introduction to AMD Instinct MI300

The AMD Instinct MI300 series is a family of high-performance accelerators designed to deliver leadership performance for generative AI workloads and HPC applications. The MI300 series is built on the 5 nm process and features the Aqua Vanjaram graphics processor. The series includes two models: the MI300A and MI300X, each with its own unique architecture and design.

Architecture and Performance

The AMD Instinct MI300 series features a advanced architecture designed to deliver high-performance and efficiency. The MI300X GPU is designed for AI inference workloads and delivers up to 1.6X more performance than the Nvidia H100. The MI300A APU provides a balanced architecture for a wide range of workloads, including AI training and HPC applications. The MI300 series also features advanced memory and storage capabilities, including high-bandwidth memory and NVMe storage.

Technical Specifications

Benchmarks and Performance Results

The AMD Instinct MI300 series has been benchmarked in a variety of workloads, including AI inference and training, as well as HPC applications. The results show that the MI300 series delivers leadership performance and efficiency, making it an ideal choice for a wide range of use cases.

What is the process node used in the AMD Instinct MI300 series?

The AMD Instinct MI300 series is built on the 5 nm process node.

What is the graphics processor used in the MI300 series?

The MI300 series features the Aqua Vanjaram graphics processor.

What is the memory and storage configuration of the MI300 series?

The MI300 series features high-bandwidth memory and NVMe storage.

What are the power consumption and form factor of the MI300 series?

The power consumption of the MI300 series is up to 250W for the MI300A and up to 300W for the MI300X. The form factor is full-height, full-length.

Specifications

Specification	MI300A	MI300X
Process Node	5 nm	5 nm
Graphics Processor	Aqua Vanjaram	Aqua Vanjaram
Memory	High-Bandwidth Memory	High-Bandwidth Memory
Storage	NVMe	NVMe
AI Inference Performance	Up to 1.2X Nvidia H100	Up to 1.6X Nvidia H100
AI Training Performance	Similar to Nvidia H100	Similar to Nvidia H100
Power Consumption	Up to 250W	Up to 300W
Form Factor	Full-Height, Full-Length	Full-Height, Full-Length